{"id":481,"date":"2026-10-24T20:18:50","date_gmt":"2026-10-24T20:18:50","guid":{"rendered":"https:\/\/wp310966.wpdns.ca\/?post_type=product&#038;p=481"},"modified":"2026-10-24T23:45:58","modified_gmt":"2026-10-24T23:45:58","slug":"slu-pp-332","status":"publish","type":"product","link":"https:\/\/aminopurecanada.ca\/product-page\/slu-pp-332\/","title":{"rendered":"SLU\u2011PP\u2011332"},"content":{"rendered":"<p><span style=\"font-weight: bold; color: #213f95;\">SLU-PP-32 is\u00a0peptide in Canada 4-Hydroxy-N-[(Z)-naphthalen-2-ylmethylideneamino<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: bold; color: #213f95;\">SLU\u2011PP\u2011332<\/span><span style=\"color: #213f95;\"> is an experimental small\u2011molecule agonist of the estrogen\u2011related receptor (ERR) family, with highest potency toward ERR\u03b1. ERRs are orphan nuclear receptors that regulate cellular energy metabolism, mitochondrial biogenesis, and oxidative capacity in metabolically active tissues.<\/span><\/p>\n<p><span style=\"color: #213f95;\">At the molecular level, SLU\u2011PP\u2011332 demonstrates high bindi<\/span>ng <span style=\"color: #213f95;\">affinity with reported EC\u2085\u2080 values of approximately 98 nM (ERR\u03b1), 230 nM (ERR\u03b2), and 430 nM (ERR\u03b3). Through ERR activation, the compound enhances transcriptional programs associated with fatty\u2011acid oxidation, mitochondrial respiration, and ATP production.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #213f95;\">In preclinical murine models, SLU\u2011PP\u2011332 functions as an \u201cexercise\u2011mimetic\u201d compound\u2014upregulating metabolic pathways typically induced by endurance activity, without requiring increased physical exertion. Current investigations focus on its potential roles in metabolic dysfunction, energy\u2011balance regulation, and mitochondrial performance.<\/span><\/p>\n<p><span style=\"color: #213f95;\">SLU\u2011PP\u2011332 is not approved for human or veterinary use. It is supplied strictly for laboratory research applications.<\/span><\/p>\n<p><span style=\"font-weight: bold; color: #213f95;\">Key Research Benefits<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: bold; color: #213f95;\">1. Potent Activation of ERR Signaling<\/span><\/p>\n<ul>\n<li><span style=\"color: #213f95;\">Engages ERR\u03b1 with nanomolar affinity, driving transcription of genes involved in energy expenditure, fatty\u2011acid oxidation, and mitochondrial biogenesis.<\/span><\/li>\n<li><span style=\"color: #213f95;\">Useful for studying nuclear\u2011receptor signaling pathways and metabolic regulation.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: bold; color: #213f95;\">2. Exercise\u2011Mimetic Metabolic Effects<\/span><\/p>\n<ul>\n<li><span style=\"color: #213f95;\">In animal studies, SLU\u2011PP\u2011332 increases mitochondrial activity in skeletal muscle and adipose tissue.<\/span><\/li>\n<li><span style=\"color: #213f95;\">Enables researchers to model exercise\u2011induced metabolic adaptations without physical activity variables.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: bold; color: #213f95;\">3. Modulation of Body\u2011Weight and Adiposity in Preclinical Models<\/span><\/p>\n<ul>\n<li><span style=\"color: #213f95;\">Obese mice exhibited significantly reduced fat accumulation (up to ten\u2011fold less) and approximately 12% lower body weight.<\/span><\/li>\n<li><span style=\"color: #213f95;\">Supports research into mechanisms of energy balance, lipid metabolism, and obesity biology.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: bold; color: #213f95;\">4. Broad Therapeutic Research Potential<\/span><\/p>\n<ul>\n<li><span style=\"color: #213f95;\">Under investigation for roles in:<\/span>\n<ul>\n<li><span style=\"color: #213f95;\">Obesity and metabolic syndrome<\/span><\/li>\n<li><span style=\"color: #213f95;\">Type 2 diabetes<\/span><\/li>\n<li><span style=\"color: #213f95;\">Non\u2011alcoholic fatty liver disease (NAFLD)<\/span><\/li>\n<li><span style=\"color: #213f95;\">Potential renal\u2011protective pathways<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"color: #213f95;\">Provides a versatile tool for studying metabolic disease mechanisms.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: bold; color: #213f95;\">5. Well\u2011Characterized Molecular Profile<\/span><\/p>\n<ul>\n<li><span style=\"color: #213f95;\">Defined ERR subtype affinities (\u03b1, \u03b2, \u03b3) allow precise receptor\u2011selectivity studies.<\/span><\/li>\n<li><span style=\"color: #213f95;\">Suitable for mechanistic work in mitochondrial physiology, oxidative metabolism, and nuclear\u2011receptor pharmacology.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: bold; color: #213f95;\">Trusted Quality<\/span><br \/>\n<span style=\"color: #213f95;\">At <\/span><span style=\"font-weight: bold; color: #213f95;\">Amino Pure Canada<\/span><span style=\"color: #213f95;\">, we supply <\/span><span style=\"font-weight: bold; color: #213f95;\">HPLC-tested peptides backed by Certificates of Analysis (COAs)<\/span><span style=\"color: #213f95;\">. With fast, nationwide shipping, SL-PP=32 is provided as a <\/span><span style=\"font-weight: bold; color: #213f95;\">research-grade peptide only<\/span><span style=\"color: #213f95;\"> for laboratory and scientific studies.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: bold; color: #213f95;\">Strictly for research Purposes<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>SLU-PP-32 is\u00a0peptide in Canada 4-Hydroxy-N-[(Z)-naphthalen-2-ylmethylideneamino &nbsp; SLU\u2011PP\u2011332 is an experimental small\u2011molecule agonist of the estrogen\u2011related receptor (ERR) family, with highest [&hellip;]<\/p>\n","protected":false},"featured_media":493,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[17],"product_tag":[],"class_list":["post-481","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/aminopurecanada.ca\/wp-json\/wp\/v2\/product\/481","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aminopurecanada.ca\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/aminopurecanada.ca\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/aminopurecanada.ca\/wp-json\/wp\/v2\/comments?post=481"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aminopurecanada.ca\/wp-json\/wp\/v2\/media\/493"}],"wp:attachment":[{"href":"https:\/\/aminopurecanada.ca\/wp-json\/wp\/v2\/media?parent=481"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/aminopurecanada.ca\/wp-json\/wp\/v2\/product_brand?post=481"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/aminopurecanada.ca\/wp-json\/wp\/v2\/product_cat?post=481"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/aminopurecanada.ca\/wp-json\/wp\/v2\/product_tag?post=481"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}